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Lancet 379(9833):22792290 American DA (2014) Standards of medical care in diabetes2014

Factors such as skin type, underlying health conditions, and current medications must be thoroughly assessed to ensure safety and efficacy

doi: 10.1056/NEJMoa1607141 39 GersteinHCColhounHMDagenaisGRDiazRLakshmananMPaisPet al

For the trial, scientists randomly assigned more than 3,000 adults who were overweight or had obesity to take one of three different doses of the experimental pill, orforglipron, or a placebo pill, for 72 weeks